Soluble endothelial protein C receptor levels in Egyptian children with beta thalassemia: Relation to hypercoagulable state
نویسندگان
چکیده
منابع مشابه
Serum Antioxidant Levels in Children with Beta-Thalassemia Major
Background: Thalassemia represents a serious health problem in Iran because of its heterogeneous frequency and the existing endogamy system. It is an inherited blood disease characterized by the under production of normal hemoglobin, the oxygen-carrying protein in red blood cells. Materials and Methods: In this study, serum antioxidants including selenium (Se), zinc (Zn) and copper (Cu) were m...
متن کاملThe hypercoagulable state in thalassemia.
Thalassemia is a congenital hemolytic disorder caused by a partial or complete deficiency of alpha- or beta-globin chain synthesis. Homozygous carriers of beta-globin gene defects suffer from severe anemia and other serious complications from early childhood. The disease is treated by chronic blood transfusion. However, this can cause severe iron overload resulting in progressive organ failure....
متن کاملLiver fibrosis in young Egyptian beta-thalassemia major patients: relation to hepatitis C virus and compliance with chelation.
BACKGROUND The main causes of liver fibrosis in transfusion-dependent thalassemia major are hepatitis C virus (HCV) infection and hepatic iron overload. The study aimed to assess liver fibrosis in Egyptian adolescents and young adult poly-transfused beta thalassemia patients infected with HCV using liver FibroScan in relation to iron overload and Liver iron concentration (LIC). MATERIAL AND M...
متن کاملPlasma levels of soluble endothelial cell protein C receptor in patients with Wegener's granulomatosis.
Elevated soluble thrombomodulin (sTM) levels are an accepted marker of endothelial damage. The physiological significance of plasma endothelial protein C receptor (sEPCR) levels is not known. To assess the relevance of this plasma protein in Wegener's granulomatosis (WG), sEPCR levels were measured in sera obtained from WG patients and related to disease activity, sTM levels, and other known ma...
متن کاملThe relation between soluble endothelial protein C receptor and factor VIII levels and FVIII/sEPCR index in healthy infants.
OBJECTIVE Both soluble endothelial protein C receptor (sEPCR) and factor VIII (FVIII) seem to be potential mediators in thrombotic and inflammatory states. The aim of the present study was to determine the relation between plasma sEPCR and FVIII levels in a group of healthy Turkish infants. METHODS The study population consisted of 50 healthy infants aged 6 months (Group 1, n=23) and 12 month...
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ژورنال
عنوان ژورنال: Pediatric Hematology Oncology Journal
سال: 2018
ISSN: 2468-1245
DOI: 10.1016/j.phoj.2018.03.002